Seyer has been CEO of Lyxor since 2006 and replaces Thibaud de Vitry, who has left Axa IM.
He started his career in 1988 at Societe Generale, which owns Lyxor, and held a variety of positions there before heading up Lyxor.
Dominique Carrel-Billiard, CEO of Axa IM, said: "We are delighted to recruit an expert of such high calibre as Laurent Seyer to further the development of our investment solutions expertise.
"It will be Laurent’s mission to keep our solutions offering at the forefront of innovation, from ALM management to multi-asset class investments and integrated funds of hedge funds solutions; as well as to increase its visibility and accelerate the commercial development of Axa IM’s solutions business."